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Index > Protein center > COL2A1(Gene name) > Bovine
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  • COL2A1 (Gene name),
  • Collagen alpha-1(II) chain (Protein name ),  CO2A1_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    COL2A1;
    Protein name:
    Collagen alpha-1(II) chain;
    Alternative:
    Alpha-1 type II collagen;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homotrimers of alpha 1(II) chains.
    Function:
    Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    1487
    Sequence:
    50:
    MIRLGAPQTL | VLLTLLVAAV | LRCHGQDVQK | AGSCVQDGQR | YNDKDVWKPE | 
    100:
    PCRICVCDTG | TVLCDDIICE | DMKDCLSPET | PFGECCPICS | ADLPTASGQP | 
    150:
    GPKGQKGEPG | DIKDIVGPKG | PPGPQGPAGE | QGPRGDRGDK | GEKGAPGPRG | 
    200:
    RDGEPGTPGN | PGPPGPPGPP | GPPGLGGNFA | AQMAGGFDEK | AGGAQMGVMQ | 
    250:
    GPMGPMGPRG | PPGPAGAPGP | QGFQGNPGEP | GEPGVSGPMG | PRGPPGPPGK | 
    300:
    PGDDGEAGKP | GKSGERGPPG | PQGARGFPGT | PGLPGVKGHR | GYPGLDGAKG | 
    350:
    EAGAPGVKGE | SGSPGENGSP | GPMGPRGLPG | ERGRTGPAGA | AGARGNDGQP | 
    400:
    GPAGPPGPVG | PAGGPGFPGA | PGAKGEAGPT | GARGPEGAQG | PRGEPGTPGS | 
    450:
    PGPAGAAGNP | GTDGIPGAKG | SAGAPGIAGA | PGFPGPRGPP | GPQGATGPLG | 
    500:
    PKGQTGEPGI | AGFKGEQGPK | GEPGPAGPQG | APGPAGEEGK | RGARGEPGGA | 
    550:
    GPAGPPGERG | APGNRGFPGQ | DGLAGPKGAP | GERGPSGLAG | PKGANGDPGR | 
    600:
    PGEPGLPGAR | GLTGRPGDAG | PQGKVGPSGA | PGEDGRPGPP | GPQGARGQPG | 
    650:
    VMGFPGPKGA | NGEPGKAGEK | GLPGAPGLRG | LPGKDGETGA | AGPPGPAGPA | 
    700:
    GERGEQGAPG | PSGFQGLPGP | PGPPGEGGKP | GDQGVPGEAG | APGLVGPRGE | 
    750:
    RGFPGERGSP | GSQGLQGARG | LPGTPGTDGP | KGAAGPAGPP | GAQGPPGLQG | 
    800:
    MPGERGAAGI | AGPKGDRGDV | GEKGPEGAPG | KDGGRGLTGP | IGPPGPAGAN | 
    850:
    GEKGEVGPPG | PAGTAGARGA | PGERGETGPP | GPAGFAGPPG | ADGQPGAKGE | 
    900:
    QGEAGQKGDA | GAPGPQGPSG | APGPQGPTGV | TGPKGARGAQ | GPPGATGFPG | 
    950:
    AAGRVGPPGS | NGNPGPPGPP | GPSGKDGPKG | ARGDSGPPGR | AGDPGLQGPA | 
    1000:
    GPPGEKGEPG | DDGPSGPDGP | PGPQGLAGQR | GIVGLPGQRG | ERGFPGLPGP | 
    1050:
    SGEPGKQGAP | GASGDRGPPG | PVGPPGLTGP | AGEPGREGSP | GADGPPGRDG | 
    1100:
    AAGVKGDRGE | TGAVGAPGAP | GPPGSPGPAG | PIGKQGDRGE | AGAQGPMGPA | 
    1150:
    GPAGARGMPG | PQGPRGDKGE | TGEAGERGLK | GHRGFTGLQG | LPGPPGPSGD | 
    1200:
    QGASGPAGPS | GPRGPPGPVG | PSGKDGANGI | PGPIGPPGPR | GRSGETGPAG | 
    1250:
    PPGNPGPPGP | PGPPGPGIDM | SAFAGLGQRE | KGPDPLQYMR | ADEAAGNLRQ | 
    1300:
    HDAEVDATLK | SLNNQIESLR | SPEGSRKNPA | RTCRDLKLCH | PEWKSGDYWI | 
    1350:
    DPNQGCTLDA | MKVFCNMETG | ETCVYPNPAS | VPKKNWWSSK | SKDKKHIWFG | 
    1400:
    ETINGGFHFS | YGDDNLAPNT | ANVQMTFLRL | LSTEGSQNIT | YHCKNSIAYL | 
    1450:
    DEAAGNLKKA | LLIQGSNDVE | IRAEGNSRFT | YTVLKDGCTK | HTGKWGKTMI | 
    1487:
    EYRSQKTSRL | PIIDIAPMDI | GGPEQEFGVD | IGPVCFL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Collagen alpha-1(II) chain
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    E0572r
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    96T
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    ELISA Kit for Bovine Collagen alpha-1(II) chain
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    E0572h
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    96T
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    ELISA Kit for Bovine Collagen alpha-1(II) chain
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    E0572m
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    Packing:
    96T
    ELISA Kit for Bovine Collagen alpha-1(II) chain
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    E0572b
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    ELISA Kit for Bovine Collagen alpha-1(II) chain
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    E0572c
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    Packing:
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    CLIA Kit for Bovine Collagen alpha-1(II) chain
    Cat.:
    U0572c
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    Packing:
    96T
    CLIA Kit for Bovine Collagen alpha-1(II) chain
    Cat.:
    U0572h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine Collagen alpha-1(II) chain
    Cat.:
    U0572m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Collagen alpha-1(II) chain
    Cat.:
    U0572b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Collagen alpha-1(II) chain
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    U0572r
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    96T
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    Polyclonal Antibody for Bovine Collagen alpha-1(II) chain
    Cat.:
    P0572Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Collagen alpha-1(II) chain
    Cat.:
    P0572Rb-r
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    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Collagen alpha-1(II) chain
    Polyclonal Antibody for Bovine Collagen alpha-1(II) chain
    Polyclonal Antibody for Bovine Collagen alpha-1(II) chain
    Cat.:
    P0572Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine Collagen alpha-1(II) chain
    Monoclonal Antibody for Bovine Collagen alpha-1(II) chain
    Monoclonal Antibody for Bovine Collagen alpha-1(II) chain
    Monoclonal Antibody for Bovine Collagen alpha-1(II) chain
    Monoclonal Antibody for Bovine Collagen alpha-1(II) chain
    Protein for Bovine Collagen alpha-1(II) chain
    Protein for Bovine Collagen alpha-1(II) chain
    Protein for Bovine Collagen alpha-1(II) chain
    Cat.:
    R0572h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Bovine Collagen alpha-1(II) chain
    Protein for Bovine Collagen alpha-1(II) chain

    R&D Technical Data
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    12% SDS-PAGE analysis

          12% SDS-PAGE analysis

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The genome sequence of taurine cattle: a window to ruminant biology and evolution."
      The bovine genome sequencing and analysis consortium
      Science324:522-528(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Hereford.
    2. 2.
      "The covalent structure of cartilage collagen. Amino acid sequence of the NH2-terminal helical portion of the alpha 1 (II) chain."
      Butler W.T. , Miller E.J. , Finch J.E. Jr.
      Biochemistry15:3000-3006(1976) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 201-362;HYDROXYLATION AT PRO-212; PRO-218; PRO-230; PRO-233; PRO-245; PRO-248; PRO-251; PRO-260; PRO-269; PRO-278; PRO-281; PRO-284; LYS-287; PRO-293; LYS-299; PRO-305; LYS-308; PRO-314; PRO-320; PRO-329; PRO-350 AND PRO-356;GLYCOSYLATION AT LYS-287; LYS-299 AND LYS-308
      tissue: Cartilage.
    3. 3.
      "The covalent structure of cartilage collagen. Evidence for sequence heterogeneity of bovine alpha1(II) chains."
      Butler W.T. , Finch J.E. Jr. , Miller E.J.
      J. Biol. Chem.252:639-643(1977) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 345-359;HYDROXYLATION AT PRO-350 AND PRO-356;VARIANT LEU-349
      tissue: Cartilage.
    4. 4.
      "Covalent structure of collagen. Amino acid sequence of an arthritogenic cyanogen bromide peptide from type II collagen of bovine cartilage."
      Seyer J.M. , Hasty K.A. , Kang A.H.
      Eur. J. Biochem.181:159-173(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 324-602;HYDROXYLATION AT PRO-329; PRO-350; PRO-356; PRO-365; PRO-368; PRO-371; LYS-374; PRO-395; PRO-398; PRO-401; PRO-410; PRO-416; LYS-419; PRO-425; PRO-431; PRO-434; PRO-440; LYS-452; PRO-458; LYS-464; LYS-470; PRO-473; PRO-482; PRO-497; PRO-506; PRO-512; PRO-518; LYS-527; PRO-530; LYS-542; PRO-551; PRO-557; PRO-566; PRO-581; PRO-587; PRO-590 AND PRO-599;GLYCOSYLATION AT LYS-374; LYS-419; LYS-452; LYS-464; LYS-470; LYS-527 AND LYS-542
      tissue: Cartilage.
    5. 5.
      "Homologous regions of collagen alpha1(I) and alpha1(II) chains: apparent clustering of variable and invariant amino acid residues."
      Butler W.T. , Miller E.J. , Finch J.E. Jr. , Inagami T.
      Biochem. Biophys. Res. Commun.57:190-195(1974) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 603-677;HYDROXYLATION AT PRO-605; LYS-608; PRO-614; LYS-620; PRO-623; PRO-626; PRO-632; PRO-644; PRO-659; PRO-668; PRO-671 AND PRO-674;GLYCOSYLATION AT LYS-608 AND LYS-620
    6. 6.
      "Characterization of the T cell determinants in the induction of autoimmune arthritis by bovine alpha 1(II)-CB11 in H-2q mice."
      Brand D.D. , Myers L.K. , Terato K. , Whittington K.B. , Stuart J.M. , Kang A.H. , Rosloniec E.F.
      J. Immunol.152:3088-3097(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 323-602
      tissue: Chondrocyte.
    7. 7.
      "Molecular definition and characterization of recombinant bovine CB8 and CB10: immunogenicity and arthritogenicity."
      Tang B. , Chiang T.M. , Brand D.D. , Gumanovskaya M.L. , Stuart J.M. , Kang A.H. , Myers L.K.
      Clin. Immunol.92:256-264(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 602-751
      tissue: Chondrocyte.
    8. 8.
      "Analysis of cDNA and genomic clones coding for the pro alpha 1 chain of calf type II collagen."
      Sangiorgi F.O. , Benson-Chanda V. , de Wet W.J. , Sobel M.E. , Ramirez F.
      Nucleic Acids Res.13:2815-2826(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1307-1487
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